Embankment promenade. Cote d'Azur: Promenade des Anglais in Nice. Attractions on the Promenade des Anglais

Hello!

I wanted to express my deep gratitude to the MAMA Clinic and all the staff for giving me the happiness of being a mother!

Many years of treatment and examinations to no avail brought us to the clinic, 2 attempts! IVF!, both successful, the first unfortunately ended in failure, but the second gave us a wonderful son! The clinic is super, there is a wonderful, responsive and professional team working there! Doctors, nurses, administrators, all at the highest level.

I would like to express my special gratitude to Fazel Irina Yuryevna, who guided me all the time, was happy and worried with me, was always in touch, and answered all my questions. The sweetest, sincere, responsive person, a great professional, with whom you always want to go for an appointment.

And also Tatyana Sergeevna Sukhacheva, a professional with capital letters, thanks to her skillful hands, we succeeded!

I am happy that I ended up in such a wonderful clinic, we recommend it to all our friends who want to find happiness in becoming parents, because in the MAMA Clinic this becomes a reality!!!

Alena was born on July 11, 2019

We would like to thank fertility doctor Fazel Irina Yuryevna for her conscientious work, for her responsiveness, attentiveness, and responsibility in her work!

For 5 years, my husband and I visited different clinics but to no avail. But after contacting the MAMA Clinic, we finally had our long-awaited baby!

Alena was born on July 11, 2019 at 21:40.

Irina Yurievna thank you very much!

M.’s family expresses their deep gratitude to the MAMA Clinic!

Thank you so much for helping and supporting us on our long, but such a joyful journey to our little happiness!

Special huge thanks to Yulia Mikhailovna Kossovich and Yaroslav Igorevich Melnik!

Without you it wouldn't exist!

Gratitude to Clinic MAMA

Many thanks to Tatyana Sergeevna!

Of course, we thank your team for our miracle.

You have fulfilled our long-awaited dream.

We were confident of a positive result with her, and that’s what happened.

Thank you for existing and helping people who need you.

Our miracle at 7 - 8 weeks!

Sincerely, our family!!!

On the second try I managed to get pregnant using the cryoprotocol!

I would like to say a huge thank you to doctor Tatyana Sergeevna Sukhacheva and the entire staff of the MAMA Clinic for their help.

In 2017 did!IVF! in this clinic, there was a combined factor of infertility, numerous diagnoses on the male and female sides.

On the second try, I managed to get pregnant using the cryoprotocol.

Before entering into the protocol, the doctor will definitely examine you comprehensively and, if there is anything that can be corrected or improved, this will definitely be done in order to maximize the chances of a successful IVF outcome.

There are no queues or a feeling of flow in the clinic, no one is in a hurry, the appointment will take as long as it takes, the protocol is also selected individually for you.

It was very touching that even after the long-awaited pregnancy, the doctor is in touch with you all the time and is ready to help and advise if necessary, although this is no longer part of his contractual responsibilities.

Special thanks to the wonderful doctor Fazel Irina Yuryevna. My pregnancy was quite difficult, so your participation, advice and support are difficult to overestimate.

Once again I would like to express my deep gratitude to the MAMA Clinic for my wonderful girl!

Thank you, “fairy godmother” of my little big happiness!

I came to the MAMA Clinic two years ago, with IVF in the long run!

I came early because I had surgery, after which the hospital gave me appointments, but I wasn’t sure if they suited my plans. By an amazing chance, I ended up with Yulia Mikhailovna Kossovich. At that time I had not seen a single review about her and was generally planning to see another doctor.

But from the first meeting I fell in love with my Doctor. Pedantic, extremely attentive to everything, in in a good way a reinsurer, at the same time an incredibly responsive person, at whose appointment you feel that he really cares what happens to you.

I was seen by Yulia Mikhailovna for a year and a half, because it was so convenient for me - to be in the hands of one doctor until the moment when I was ready for IVF.

We adjusted hormonal therapy after surgery, then monitored the capricious endometrium, and in April 2019, when my husband and I were ready, we entered into the protocol. Due to hyperstimulation, I had to come three times for an IV; the transfer, of course, was cancelled, but I was mentally prepared for this, because Yulia Mikhailovna, observing me during the stimulation process, warned that with such a response of the ovaries this would most likely happen .

As a result, the transfer took place through the cycle, in June. Quietly, calmly, with a smile, in absolute comfort, Yulia Mikhailovna made the transfer to me, handing me the first photo of my child.

Throughout the long period of waiting for the first ultrasound, Yulia Mikhailovna is always in touch. And since then, on any issue, while in confinement, being observed in another clinic (after 12 weeks), I always know that my Doctor is in touch, will always support with a word and help with advice.

Thank you, “fairy godmother” of my little big happiness! I don’t know what providence brought me to the MAMA Clinic, about which I had not heard a word until September 2017. But from the security guard to every employee - absolutely everyone is friendly, ready to help, support, be it tea after I got seasick in a traffic jam, be it the desire to walk me to the car after a No-shpa injection, be it just sweet Nothing- all this, not to mention the highest professionalism of everyone with whom I came into contact, made the entire period of preparation and implementation of IVF completely comfortable.

Prosper, my dears! I’ll come back to you in a few more years to get my daughter!

Mycoplasma and ureaplasma are infections that can be asymptomatic. These microorganisms cause serious diseases of the genitourinary system and respiratory tract. They are especially dangerous for pregnant women as they can affect correct flow pregnancy, cause polyhydramnios and premature birth. With the disease, the risk of infection of the fetus increases sharply.

What are mycoplasma and ureaplasma?

The mycoplasma family (Mycoplasmaсea) has more than 100 varieties. Most large group occupied by mycoplasmas - more than 100 species. Ureaplasma has only five varieties.

Not all mycoplasmas are capable of causing diseases of the respiratory tract and genitourinary system. The most dangerous among them are only three varieties: Mycoplasma genitalium (Mycoplasma genitalium), Mycoplasma hominis (Mycoplasma hominis), Mycoplasma pneumoniae (Mycoplasma pneumoniae), among ureaplasmas there are two varieties: Ureaplasma parvum (ureaplasma parvum), Ureaplasma urealyticum (ureaplasma urealyticum).

The detection of ureaplasma and mycoplasma does not always indicate the presence or development of a particular disease. Scientists have proven that these microorganisms can be natural environment human body. As a percentage, in healthy women leading a normal sex life, ureaplasma is detected in 40%, mycoplasma in 20%. Men are less likely to become carriers of these microorganisms. Mycoplasmas can also be found in the mucous membranes of children, as well as in adults who are not sexually active. Often microorganisms do not manifest themselves during life. And only when certain conditions arise for the proliferation of mycoplasmas (for example, decreased immunity, changes in the natural flora of the body) may symptoms of the disease appear.

Symptoms of the disease

When microorganisms mycoplasma and ureaplasma multiply, women often develop acute symptoms in the genital organs, and curdled mucus is released from the vagina. Pain may occur during sexual intercourse and be accompanied by. Microorganisms also provoke nagging discomfort in the lower abdomen, pain in the lower back and joints.

In men, the following symptoms are possible: itching and burning of the genital organ, which is aggravated by sexual intercourse or urination; and impaired sperm quality, pain in the groin area.

The incubation period for the reproduction of mycoplasmas and ureaplasmas is about 3-4 weeks after the suspected infection, so symptoms may not appear immediately, but after several weeks.

If you notice the manifestation of certain symptoms in yourself, immediately contact a gynecologist for women, or a urologist for men. The doctor will order tests. To determine the presence or absence of microorganisms, a smear is taken from the cervical canal or urethra. Since ureaplasma and mycoplasma do not have a cell membrane, they are insensitive to most drugs. To determine their sensitivity to antibiotics, an additional test is required.

Routes of infection with mycoplasmas and ureaplasmas

The main route of infection is through the mucous membrane of the body. Infection occurs mainly through sexual contact, including oral sex, so mycoplasmosis and ureaplasmosis are often classified as STDs (sexually transmitted diseases).

Infection of children occurs vertically, i.e., even during pregnancy, microorganisms penetrate the placenta and infect the fetus. In addition, a child can become infected during the birth process when passing through the birth canal. If the presence of microorganisms is detected in a woman during pregnancy, after childbirth all the necessary tests are taken from the baby and treatment is prescribed.

Many doctors say that mycoplasma infection can occur through household contact. But this is unlikely. Infection occurs when people for a long time share personal hygiene items.

Ureaplasma is the cause of miscarriage (miscarriages)

During pregnancy, as well as during its planning, gynecologists recommend taking a test for ureaplasma in order to prescribe treatment in a timely manner. Do not forget that these microorganisms are opportunistic; they do not always cause damage to health. Mycoplasmas can exist hidden in the human body, but when favorable conditions arise for them, they begin to actively multiply. During pregnancy, a woman’s immunity sharply decreases, the body stops fighting microorganisms, allowing the disease to enter the acute stage. Exacerbation of mycoplasmas during pregnancy can lead to serious consequences - infection of the fetus through the placenta and miscarriage. The risk of infection of the child during childbirth also increases.

Why does the likelihood of miscarriage increase sharply with ureaplasma? During pregnancy, microorganisms begin to destroy the cervix, it softens and becomes loose, which leads to early opening of the pharynx and provokes early birth and miscarriages. To avoid the harmful effects of ureaplasma on the cervix, the doctor prescribes appropriate treatment. If the opening of the uterine pharynx begins to occur, in this case only sutures will help.

Treatment of ureaplasma during pregnancy

When ureaplasma is detected in the body of a pregnant woman, the question arises about treating the disease. Here a pregnant woman may encounter a problem: there are opposing opinions from doctors. Some of them believe that treatment is mandatory, some (mainly adherents of European views on medicine) believe that if ureaplasma is not in the active stage, it does not need to be treated. In order to determine the activity of ureaplasma in the body of a pregnant woman, the doctor prescribes additional tests. If there are no complications or threat of miscarriage, treatment is prescribed after 30 weeks. At this time, there is the least risk of negative effects of the drug on the fetus. After treatment, a woman can be sure that the child will not become infected when passing through the birth canal. If there is a threat of miscarriage, treatment is prescribed immediately. The doctor selects the medications individually for each woman. Do not forget that both sexual partners should be treated.

Stages of treatment of ureaplasma during pregnancy

Treatment of ureaplasma is prescribed by a gynecologist and is carried out under his strict supervision. You should not self-medicate, as this can harm the health of the mother and child. Treatment usually takes place in several stages:

1. stage. Detection of ureaplasma. If a patient is suspected of having ureaplasma, and may also be routinely prescribed tests for the presence of microorganisms. When ureaplasma is detected, the doctor usually prescribes an additional examination to determine its sensitivity to antibiotics.
2. stage. If the disease is detected early in pregnancy, the doctor may prescribe an immunomodulatory drug. For example, Viferon. This medicine can be used after the 14th week of pregnancy, it improves the mother's immunity and increases the body's resistance to the effects of ureaplasma. Viferon does not provide negative influence on the health of mother and child.
3. stage. Antiviral drugs. Antibacterial treatment is prescribed after 20 weeks. Modern medicine makes it possible to select an antibiotic for the treatment of ureaplasma that causes minimal harm to the fetus. The doctor prescribes medicine individually for each woman, taking into account the characteristics of her body, the sensitivity of microorganisms to antibiotics and the degree of their spread.

The danger of mycoplasmas during pregnancy

Treatment of mycoplasmosis during pregnancy

Treatment of mycoplasmosis in pregnant women occurs only as prescribed by a doctor and under his strict supervision. The risk to the patient's fetus occurs if the count of microorganisms per 1 ml exceeds 100 CFU. At low rates Treatment is usually not prescribed.

Before selecting the necessary medication, the doctor sends the woman for an additional test, which reveals the sensitivity of microorganisms to antibiotics. Macrolide antibiotics are most often prescribed. They have the least effect on the fetus and are effective in the treatment of mycoplasmosis. Antibiotics are usually prescribed after 12 weeks of pregnancy when all the main organs of the child are formed. The course of treatment is short, but most effective. The disease rarely recurs. Usually, in addition to antibiotics, the doctor prescribes immunomodulatory agents to increase a woman’s immunity. Often during pregnancy, the body's protective properties are reduced, allowing microorganisms to actively multiply. The success of treatment depends on the state of the pregnant woman’s immunity.

Treatment of mycoplasmosis must be carried out in both sexual partners, as treatment is carried out in men in the articles.

Mycoplasmosis and ureaplasmosis, consequences for pregnant women.

Mycoplasmosis and ureaplasmosis are dangerous during pregnancy for both the mother and the fetus. Diseases can provoke initial stage during pregnancy, improper attachment of the placenta. Microorganisms can infect the walls of the uterus and penetrate the placenta to the fetus. On early stages the risk of miscarriage increases dramatically, since due to inflammation the uterus enters a state of tone. Also, ureaplasma and mycoplasma cause looseness of internal tissues, the cervix softens and begins to open, which can cause miscarriage. For the same reasons, more later the disease can provoke early labor.

After childbirth, endometritis of the uterus often occurs due to the inflammatory process. People called it “puerperal fever.”

If during pregnancy, tests reveal the microorganisms of mycoplasmosis and ureaplasmosis in their active form, the doctor will prescribe the necessary medications. You should not neglect them, because timely treatment will help avoid the unpleasant consequences of diseases.

During the period of bearing a baby, a woman must undergo tests for TORCH infections. Ureaplasmosis and mycoplasmosis during pregnancy pose a great threat to the normal intrauterine development of the fetus.

What kind of diseases are these?

Mycoplasma and ureaplasma are bacteria; they lack a cell membrane. Because of the latter property, their diagnosis and treatment becomes more complicated. They penetrate the human mucous membranes and actively multiply in the genital and respiratory organs.

Some strains of mycoplasmas and ureaplasmas provoke the development of pathologies of the genitourinary system. It is worth noting that these microorganisms belong to the natural microflora of humans and their detection in a blood test does not always indicate the presence of an infectious process.

The majority of carriers of ureaplasma and mycoplasma are women; in men, these pathogens are very rare. They remain in a latent state for a long time and become highly active when the immune system is weakened.

Transmission routes

The main routes of infection into the body are through sexual intercourse (unprotected sexual intercourse). In this case, the pathogen invades the epithelial layer of the uterus and begins to reproduce there. IN to a greater extent mycoplasma and ureaplasma affect the muscle layer in the organ.

Mycoplasmosis and ureaplasmosis during pregnancy are classified as a group. The likelihood of transmitting a pathogen during oral sex is very high, so it is important to follow all the rules of protection during intimate intimacy.

Reasons for the development of pathology

Since these microorganisms are part of the natural microflora, there must be reasons for their proliferation. Ureaplasmas have the property of breaking down urea, thereby causing ureaplosis.

This occurs in the presence of other pathogenic microorganisms (chlamydia, gonococci, etc.) or dysbacteriosis in the body. The impetus for this process is a weakened immune system, non-compliance with personal hygiene rules, poor nutrition, vitamin deficiency, etc.

Often mycoplasmosis and ureaplasmosis in women develop against the background of severe hypothermia, frequent stress, after gynecological operations, etc. The impetus for the active growth of pathogens is the period of pregnancy itself.

Early onset of sexual activity, frequent change of sexual partners, unprotected intimate life increase the chances of infection with pathogens of ureaplasmosis and mycoplasmosis. These diseases occur among women of reproductive age. Delayed treatment increases the chances of developing complications (gynecological diseases, infertility, etc.).

Main symptoms

In the initial stage, the infection does not manifest itself in any way. As the pathogen multiplies, symptoms such as burning and pain below during urination occur.

A woman discovers she has a discharge white, reminiscent of cottage cheese (very often the initial stages of diseases are mistaken for banal).

Symptoms of ureaplasmosis and mycoplasmas are as follows:

• compactions and nagging pain that radiates to the lower back;
• during and after the end of sexual intercourse;
• disturbance of the urination process.

The incubation period of pathogens is 21-30 days. That is why signs do not appear immediately, but as a certain concentration of microorganisms accumulates.

Danger for pregnant women

The impact of these diseases on a woman’s health is colossal. Mycoplasmas and ureaplasmas increase the chances of developing urethritis and other diseases of the genitourinary system. Also, these microorganisms contribute to the development of polyhydramnios and reduce the muscle tone of the uterus (fraught with early miscarriages or premature birth).

When planning a pregnancy, every woman should undergo blood tests to detect these microorganisms. Early diagnosis increases the chances of positive result treatment. Ureaplasma causes inflammation of the endometrial layer in the uterus, especially in the postpartum period.

Danger to child

These diseases cause serious consequences for the fetus. Doctors diagnose intrauterine development disorders; the baby often becomes infected during childbirth. Long-term presence of pathogens in a dormant form leads to intrauterine infection of the fetus.

Of particular danger is the addition of chlamydia or gonococci (the consequences for the child can be expressed in mental retardation, disruption of work internal organs and systems).

Importance of diagnosis

Experts recommend that every woman planning her pregnancy be tested for these types of infections. This will allow the disease to be identified early stage and provide effective treatment.

For research, venous blood and smears from the vagina and cervix are used. The most informative method is the PCR method, thanks to which you can get a complete picture of the patient’s condition. It is recommended that the woman’s sexual partner undergo a similar diagnosis.

Treatment methods

Therapeutic measures are selected depending on the type of pathogen and the stage of development of the disease (the duration of pregnancy must be taken into account, in some cases the woman is offered an artificial termination). A feature of ureaplasmosis and mycoplasmosis is their resistance to many groups of antibacterial drugs (penicillin, cephalosporin and other groups).

Treatment of ureaplasmosis during pregnancy includes taking medications that help restore the vaginal microflora. For this purpose, antibiotics from the group of tetracyclines and macrolides are used.

Treatment necessarily includes the use of immunomodulators, which strengthen the patient’s immunity. To prevent concomitant infection, drugs from the group of antiprotozoal and antifungal drugs are used.

The woman must be prescribed probiotics, which normalize the microflora in a short time. Therapy for pregnant women is carried out up to 22 weeks (this reduces the chances of intrauterine infection).

Mycoplasma and ureaplasma are bacteria that are found in the genitourinary organs of some people and can cause symptoms of inflammation, as well as problems with conceiving a child and carrying a pregnancy.

For women planning pregnancy or already pregnant, highest value have the following types of mycoplasmas and ureaplasmas:

• Mycoplasma hominis
• Mycoplasma genitalium
• Ureaplasma urealyticum
• Ureaplasma parvum

It is these types of bacteria that can affect the course of pregnancy and sometimes cause infertility.

Planning pregnancy with mycoplasma

This section contains answers from gynecologists to frequently asked questions from women planning a pregnancy.

Do I need to be tested for mycoplasma and ureaplasma before planning a pregnancy?

It is believed that not all women need to be tested for mycoplasma and ureaplasma when planning pregnancy. Most doctors recommend testing for these infections only in the following cases:

• if you have had several sexual partners with whom you have had unprotected sex
• if showed inflammation of the urethra, vagina or cervix of unknown cause
• if you have previously had several or consecutive miscarriages
• if you have been unable to get pregnant for more than a year and the reason is unknown
• if you have or have ever had symptoms of pyelonephritis (frequent urination, lower back pain, increased body temperature, increased white blood cells in the urine)
• if you have been diagnosed with sexually transmitted infections (, etc.)
• if you often “exacerbate”

All of the above circumstances may indicate that you have mycoplasma and ureaplasma, which means that before planning a pregnancy it is better to get tested for these infections. It is available on our website.

Previously, I was diagnosed with mycoplasma and ureaplasma, I did not receive any treatment and now I am planning a pregnancy. What do we have to do?

In this situation, you need to take repeated tests for mycoplasma and ureaplasma and visit a gynecologist with the results of the analysis.

It is possible that since the last analysis, your immune system has overcome this infection and now mycoplasma and ureaplasma are no longer present, or their quantity does not pose a threat to a future pregnancy.

If tests for mycoplasma and ureaplasma are positive, then you and your partner may need treatment before planning a pregnancy.

Do I need to treat mycoplasmas and ureaplasmas before pregnancy?

Not always. Mycoplasmas and ureaplasmas in some women are part of the normal microflora and do not pose a threat to pregnancy.

Treatment may be required only in certain cases if:

• a smear on the flora or other examination methods revealed an inflammatory process in the genitourinary organs
• if cultures for M. hominis or Ureaplasma spp. showed a titer of 10*4 CFU/ml and higher
• if M. genitalium was detected
• if you have previously had 2 or more miscarriages or in a row
• if you have infertility and the cause is unknown

Does my partner need treatment?

Not always either. Treatment is necessary for a sexual partner if M. genitalium is detected in him, or if mycoplasma or ureaplasma causes symptoms of urethritis (burning and pain during urination, discharge from the urethra, redness of the external urethral opening, etc.)

Also, your sexual partner may need treatment if he has no complaints, but you have problems conceiving and bearing a child (infertility of unknown cause, 2 or more miscarriages in a row).

Can mycoplasmas and ureaplasmas lead to infertility?

This fact has not yet been scientifically proven. Mycoplasma and ureaplasma are sometimes found in women suffering from infertility, but it has not yet been possible to establish a direct connection between these infections and the inability to conceive a child.

Mycoplasma or ureaplasma can be considered the cause of infertility if all other tests are normal and the only abnormality that was found is these infections. In this case, a course of antibacterial treatment may increase the chances of pregnancy.

Mycoplasma or ureaplasma sometimes cause inflammation of the fallopian tubes () and provoke the formation of adhesions. Adhesions in can lead to their obstruction, and therefore to infertility or. To check if your fallopian tubes are clear, your doctor may recommend

Pregnancy with mycoplasma

This section contains answers from gynecologists to frequently asked questions from pregnant women who have been diagnosed with mycoplasma or ureaplasma.

I am pregnant and have been diagnosed with mycoplasma/ureaplasma. Is it dangerous?

Mycoplasmas and ureaplasmas can affect the course of pregnancy. Pregnant women who have been diagnosed with mycoplasma or ureaplasma have an increased risk of the following complications:

• threat of miscarriage;
• and miscarriage in the first or second trimester of pregnancy;
• inflammation of the vagina and cervix during pregnancy;
• premature rupture of amniotic fluid;
• birth of a child with low body weight (less than 2500g);
• increased body temperature after childbirth (puerperal fever).

Can mycoplasma or ureaplasma cause miscarriage?

Yes, these bacteria can cause miscarriage. Most high risk miscarriage is observed if the pregnant woman has signs. Treatment helps reduce the risk of miscarriage.

Can mycoplasma or ureaplasma harm an unborn child?

Unfortunately, it can. If mycoplasma and ureaplasma were detected in a pregnant woman, then the unborn child has an increased risk of congenital mycoplasmosis, which is manifested by pneumonia, meningitis, prolonged jaundice and other disorders.

Is it necessary to treat mycoplasma/ureaplasma during pregnancy?

Treatment during pregnancy is not always necessary. Your doctor may prescribe antibiotics if you have signs of inflammation, bacterial vaginosis, are at risk of miscarriage, or if M. genitalium is detected. Treatment of M. hominis or Ureaplasma spp. it is required only if their number exceeds the permissible values: if the culture showed a titer of 10*4 CFU/ml or higher.

What antibiotics are prescribed to pregnant women for mycoplasma/ureaplasma? Are they dangerous for the child?

For some reason, it so happened that most gynecologists in our country prescribe the drug Vilprafen to pregnant patients with mycoplasmosis or ureaplasmosis ( international name Josamycin). This drug is believed to be safe during pregnancy, but there is no scientific evidence to support this yet. The drug has been studied too little, and the risks of treatment with Vilprafen during pregnancy are not yet known.

All over the world, another drug is prescribed for the treatment of mycoplasma or ureaplasma during pregnancy - Azithromycin. The effect of Azithromycin on the course of pregnancy and on the health of the unborn child has been well studied in large studies. This drug is approved for use in pregnant women.

How long does the treatment last?

The duration of treatment depends on many different factors and is determined by the attending physician. The average duration of taking antibiotics is 5-7 days, but sometimes treatment can take 2 weeks.

After completing the course of treatment, you will need to undergo repeated tests to check whether the medications were effective.